
Cancer Straight Talk Podcast
Cancer Straight Talk from Memorial Sloan Kettering is a podcast about cancer that brings together patients and experts, to have straightforward evidence-based conversations. Dr. Diane Reidy-Lagunes hosts this cancer podcast with a mission to educate and empower cancer patients and their family members.
If you have questions, feedback, or topic ideas for upcoming episodes, please e-mail us at: [email protected]

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A Game-Changing Cancer Drug Gives Stage 4 Breast Cancer Patients New Hope
For nearly half of all breast cancer patients – those with low levels of the HER2 protein – targeted treatment options have always been limited. Palliative chemo has been the standard of care in stage 4 metastatic patients – until now.

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Finding Hope and Acceptance in a Cancer Diagnosis: One Couple’s Advice
You’ve received a cancer diagnosis. Now what? For George Kolasa, it was obvious: use his glioblastoma diagnosis for good. “I’ve been chosen."

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Breakthrough Rectal Cancer Drug Trial: What It Means For You
A recent clinical trial for rectal cancer headed up by Memorial Sloan Kettering has grabbed the attention of medical oncologists and cancer scientists around the world. Like a miracle, in a subset of patients with the right genetic makeup, an IV infusion of an immunotherapy caused a complete remission. The doctors were shocked. The cancer disappeared in every single patient enrolled on trial. The results are so impressive they were published in The New England Journal of Medicine and featured at the nation’s largest gathering of clinical oncologists in June 2022.

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The Cost of Cancer: Advice on Insurance, Planning and Paying for Treatment
One of the most universal and devastating side effects of cancer is financial toxicity. Learn tips for choosing the right insurance plan, oral versus IV treatments, planning ahead and resources for aid.

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What’s the Hash on the Little Green Plant and Cancer?
What makes a good pain remedy– chemically, mentally, legally? Is it better as an edible, oil or vapor? How does one even begin to figure out dosing?

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The Day I Couldn't Sing: Rock Star Andrew McMahon on Surviving the Identity Crisis of Cancer
Andrew and his wife, Kelly, talk about their struggle to save not just Andrew’s life but also their marriage and personal identities.

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A Man’s Guide to Sex and Cancer
Learn about the impacts of cancer and its treatment on men’s sexual health, and get advice for regaining sexual function.

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How Does Cycling Fight Cancer? Dave Linn & Ethan Zohn on the Power of Cycle for Survival
Every year, tens of thousands of people across the country hop on stationary bikes to raise money for rare cancer research. How did this phenomenon start? And who is that money helping?

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Gratitude, Grief and Why You Don't Have to Choose
How does one find gratitude while living with cancer? Can gratitude and grief exist at the same time? Hear past guests of the podcast share what they're grateful for, and learn some tools for managing your grief.

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The Future of Cancer Drugs: A Conversation with Dr. Charles Sawyers
In this episode, Dr. Diane Reidy-Lagunes talks with Dr. Sawyers about what’s next in the field of cancer pharmaceuticals. Is another silver bullet on the horizon?